The historical Pamir Highway, officially called M41, is an excellent challenge for a 4x4 adventure travelers. Most of the road is paved, except for the mountain passes, and the length of the road is 2.038 km kilometers linking Termez (Uzbekistan) and Kara-Balta (Kyrgyzstan) going through the Pamir Mountains. The road is heavily damaged in places by erosion, earthquakes, landslides, and avalanches.

Kyzylart Pass is an international high mountain pass at an elevation of 4.280m (14,042ft) above the sea level, located on the border of Tajikistan and Kyrgyzstan.

Located in the Sughd Region of Tajikistan, the Anzob Tunnel is said to be the most dangerous tunnel in the world. Called the Tunnel of Fear and the Tunnel of Death by locals, it lacks proper lighting and ventilation, breathing is hard and painful due to the thick mixture of exhaust gases.

Anzob Pass is a high mountain pass, at an elevation of 3.372m (11,062ft) above the sea level, located northwest of Tajikistan's capital Dushanbe. The pass is located between Dushanbe and Samarkand and there’s a weather observation station located at the pass top. The climb is a series of narrow zigzags, with some impressive drops to the valley below.

Karakul Lake is a high mountain lake at an elevation of 3.900m (12,800ft) above the sea level, located in the Pamir Mountains in Tajikistan.

Pereval Tagarkaty is a high mountain pass at an elevation of 4.160m (13,648ft) above the sea level, located within the Badakhshan National Park, in the Pamir Mountains of Gorno-Badakhshan Autonomous Region, Tajikistan.

Ak-Baital Pass is a high mountain pass on the border of the Republic of Tajikistan (GBAO region) and Kyrgyzstan at an elevation of 4.655m (15,270ft) above the sea level. It is a part of the Trans-Alay Range and it’s the highest road pass in the former Soviet Union.

Koitezyak Pass is a high mountain pass at an elevation of 4.122m (13,523ft) above the sea level, located within the Badakhshan National Park, in the Pamir Mountains of Gorno-Badakhshan Autonomous Region, Tajikistan.

Pereval Shakhristan is an international high mountain pass at an elevation of 3.382m (11,095ft) above the sea level, located on the Tajikistan-Uzbekistan border. Drive with care as this is a mountain road with hairpin curves and dangerous dropoffs.

Khargush Pass is a high mountain pass at an elevation of 4.344m (14,251ft) above the sea level, located in the Kūhistoni Badakhshon Autonomous Region, in eastern Tajikistan. The climb sits in an isolated environment of dramatic beauty.

Pereval Nayzatash is a high mountain pass at an elevation of 4.134m (13,562ft) above the sea level, located within the Badakhshan National Park, in the Pamir Mountains of Gorno-Badakhshan Autonomous Region, Tajikistan.

Pereval Oburdon is a high mountain pass at an elevation of 3.902m (12,801ft) above the sea level located in Sughd Region, in the northwest of Tajikistan.

Kulma Pass is an international high mountain pass, at an elevation of 4.362m (14,311ft) above the sea level, located across the Pamir Mountains, on the China–Tajikistan border.

Kök Jar Pass is a high mountain pass at an elevation of 3.807m (12,490ft) above the sea level, located in the Kūhistoni Badakhshon Autonomous Region, in eastern Tajikistan. The road may be impassible at times even by 4×4 vehicles.

The Khujand-Dushanbe road is an amazing journey in the mountains of Tajikistan. Part of the M-34 highway, the road links Duschanbe, the capital of the country, and Khujand, the country's second largest city.

Khaburabot Pass is a high mountain pass at an elevation of 3.852m (12,637ft) above the sea level, located on the Pamir Mountains, in Tajikistan. The pass is traversed by the Pamir Highway. Drive with care as this is an extreme mountain road with hairpin curves and dangerous dropoffs.

The Kurgush pass is a high mountain pass at an elevation of 4.083m (13,395ft) above the sea level, located within the Badakhshan National Park, in the Pamir Mountains of Gorno-Badakhshan Autonomous Region, Tajikistan.

Lake Iskander-kul is an alpine lake of glacial origin at an elevation of 2.242m (7,355ft) above the sea level, located in Sughd province, in western Tajikistan.

Murghab is a high mountain town at an elevation of 3.618m (11,869ft) above the sea level, located on the Murghab Plateau in eastern Tajikistan (Gorno-Badakhshan Autonomous Oblast). It’s one of the highest towns accessible by car on Earth.

Located in southern Tajikistan, the Khudkham River bridge is one of the most spectacular bridges in the world. The bridge is 28m long.

Yashikul lake is a fresh-water alpine lake at an elevation of 3.976m (13,044ft) above the sea level, located in Gorno-Badakhshan Autonomous Province, in southeast Tajikistan.

Located in southern Tajikistan, the Kulob-Qal'ai Khumb road is a very challenging experience following the Afghan border closely along the Panj river. This road has humbled many egos. It’s not for the sissies and shouldn’t be attempted by novice drivers.